Complete Genome Sequence of the Complex Carbohydrate-Degrading Marine Bacterium, Saccharophagus degradans Strain 2-40T

نویسندگان

  • Ronald M. Weiner
  • Larry E. Taylor
  • Bernard Henrissat
  • Loren Hauser
  • Miriam Land
  • Pedro M. Coutinho
  • Corinne Rancurel
  • Elizabeth H. Saunders
  • Atkinson G. Longmire
  • Haitao Zhang
  • Edward A. Bayer
  • Harry J. Gilbert
  • Frank Larimer
  • Igor B. Zhulin
  • Nathan A. Ekborg
  • Raphael Lamed
  • Paul M. Richardson
  • Ilya Borovok
  • Steven Hutcheson
چکیده

The marine bacterium Saccharophagus degradans strain 2-40 (Sde 2-40) is emerging as a vanguard of a recently discovered group of marine and estuarine bacteria that recycles complex polysaccharides. We report its complete genome sequence, analysis of which identifies an unusually large number of enzymes that degrade >10 complex polysaccharides. Not only is this an extraordinary range of catabolic capability, many of the enzymes exhibit unusual architecture including novel combinations of catalytic and substrate-binding modules. We hypothesize that many of these features are adaptations that facilitate depolymerization of complex polysaccharides in the marine environment. This is the first sequenced genome of a marine bacterium that can degrade plant cell walls, an important component of the carbon cycle that is not well-characterized in the marine environment.

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عنوان ژورنال:
  • PLoS Genetics

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2008